SCHEMBL29640388

SCHEMBL29640388

CSCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCCN)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.65
▸ GLP1R P43220 3/20 0.63
▸ GCGR P47871 1/20 0.63
▸ GIPR P48546 1/20 0.63
▸ RXFP1 Q9HBX9 4/20 0.61
▸ PTH1R Q03431 3/20 0.59
▸ BACE1 P56817 1/20 0.59
▸ VIPR1 P32241 1/20 0.59
▸ CCKBR P32239 1/20 0.59
▸ ECE1 P42892 1/20 0.58
▸ MUS81 Q96NY9 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31182903 0.95 TFPI (0.65) TFPIGLP1RGCGRGIPRRXFP1
SCHEMBL30277897 0.95 TFPI (0.60) TFPIGLP1RGCGRGIPRRXFP1
Misgurin SCHEMBL29509599 0.93 TFPI (0.72) TFPIGLP1RGCGRGIPRRXFP1
SCHEMBL30607324 0.93 VIPR1 (0.65) GLP1RGCGRGIPRRXFP1PTH1R
SCHEMBL31678895 0.93 TFPI (0.60) TFPIGLP1RGCGRGIPRRXFP1
SCHEMBL29949376 0.92 GLP1R (0.63) TFPIGLP1RGCGRGIPRRXFP1
SCHEMBL30194463 0.92 TFPI (0.66) TFPIGLP1RGCGRGIPRRXFP1
SCHEMBL30658242 0.92 TFPI (0.66) TFPIGLP1RGCGRGIPRRXFP1
SCHEMBL30432173 0.92 VIPR1 (0.69) TFPIGLP1RGCGRGIPRPTH1R
SCHEMBL29551264 0.92 TFPI (0.71) TFPIGLP1RPTH1RVIPR1ECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125365-A1 TRIAZINE DERIVATIVES HAVING VIRUS REPLICATION INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME SHIONOGI & CO., LTD. (JP) 2026-05-07 — — US disclosed
US-12559474-B2 Triazine derivatives having virus replication inhibitory activity and pharmaceutical composition comprising the same SHIONOGI & CO., LTD. (JP) 2026-02-24 — — US disclosed
US-12545687-B2 Uracil derivatives having virus replication inhibitory activity and pharmaceutical composition comprising the same SHIONOGI & CO., LTD. (JP) 2026-02-10 — — US disclosed
EP-4122926-B1 TRIAZINE DERIVATIVES HAVING VIRUS REPLICATION INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME SHIONOGI & CO (JP) 2025-06-04 — — EP disclosed
CN-119818502-A Pharmaceutical composition containing triazine derivative 盐野义制药株式会社 2025-04-15 — — CN disclosed
WO-2025074997-A1 CONDENSED HETEROCYCLIC DERIVATIVE HAVING VIRAL PROLIFERATION INHIBITORY ACTIVITY, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 塩野義製薬株式会社 2025-04-10 — — WO disclosed
US-20250099474-A1 PHARMACEUTICAL FOR TREATMENT OF NOVEL CORONAVIRUS INFECTION SHIONOGI & CO., LTD. (JP) 2025-03-27 — — US disclosed
US-20250092056-A1 URACIL DERIVATIVES HAVING VIRUS REPLICATION INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME SHIONOGI & CO., LTD. (JP) 2025-03-20 — — US disclosed
EP-4506342-A1 URACIL DERIVATIVE HAVING VIRAL GROWTH INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Shionogi & Co., Ltd (JP) 2025-02-12 — — EP disclosed
US-20250025459-A1 COVID-19 TREATMENT MEDICINE CHARACTERIZED BY COMBINING 3CL PROTEASE INHIBITOR AND COVID-19 TREATMENT DRUG SHIONOGI & CO., LTD. (JP) 2025-01-23 — — US disclosed
WO-2023054732-A2 PHARMACEUTICAL FOR TREATING NOVEL CORONAVIRUS INFECTION 塩野義製薬株式会社 2023-04-06 — — WO disclosed
WO-2023054292-A1 PHARMACEUTICAL COMPOSITION CONTAINING TRIAZINE DERIVATIVE 塩野義製薬株式会社 2023-04-06 — — WO disclosed
CN-115850249-A Triazine derivatives having virus proliferation inhibitory activity and pharmaceutical composition containing the same 盐野义制药株式会社 2023-03-28 — — CN disclosed
WO-2023042879-A1 BICYCLIC HETEROCYCLIC DERIVATIVE HAVING VIRAL GROWTH INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 塩野義製薬株式会社 2023-03-23 — — WO disclosed
WO-2023033098-A1 BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE HAVING VIRUS GROWTH INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 塩野義製薬株式会社 2023-03-09 — — WO disclosed
WO-2023027198-A1 PREPARATION FOR ORAL ADMINISTRATION CONTAINING TRIAZINE DERIVATIVE 塩野義製薬株式会社 2023-03-02 — — WO disclosed
EP-4122926-A1 TRIAZINE DERIVATIVE HAVING VIRUS PROPAGATION INHIBITORY EFFECT, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Shionogi & Co., Ltd (JP) 2023-01-25 — — EP disclosed
CN-115038696-A Triazine derivatives having virus proliferation inhibitory activity and pharmaceutical composition containing the same 盐野义制药株式会社 2022-09-09 — — CN disclosed
WO-2022138987-A1 TRIAZINE DERIVATIVE HAVING VIRUS PROPAGATION INHIBITORY EFFECT, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 塩野義製薬株式会社 2022-06-30 — — WO disclosed
WO-2022138988-A1 TRIAZINE DERIVATIVE HAVING VIRUS PROPAGATION INHIBITORY EFFECT, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 塩野義製薬株式会社 2022-06-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250099474-A1 PHARMACEUTICAL FOR TREATMENT OF NOVEL CORONAVIRUS INFECTION ACE, ACE2, TMPRSS2 TFPI 31/4885GLP1R 2160/4885GCGR 2888/4885
US-20250092056-A1 URACIL DERIVATIVES HAVING VIRUS REPLICATION INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME ACE, SARS1, RNASEL TFPI 864/4885GLP1R 1031/4885GCGR 2495/4885
US-12559474-B2 Triazine derivatives having virus replication inhibitory activity and pharmaceutical composition comprising the same NSUN2, ZC3HAV1, IFNAR1 TFPI 4220/4885GLP1R 2151/4885GCGR 1493/4885
US-20250025459-A1 COVID-19 TREATMENT MEDICINE CHARACTERIZED BY COMBINING 3CL PROTEASE INHIBITOR AND COVID-19 TREATMENT DRUG ACE, ACE2, TMPRSS2 TFPI 142/4885GLP1R 188/4885GCGR 1012/4885
US-12545687-B2 Uracil derivatives having virus replication inhibitory activity and pharmaceutical composition comprising the same SARS1, ACE, ACE2 TFPI 801/4885GLP1R 2773/4885GCGR 3970/4885
US-20260125365-A1 TRIAZINE DERIVATIVES HAVING VIRUS REPLICATION INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME ACE2, ACE, SARS1 TFPI 1168/4885GLP1R 1472/4885GCGR 1869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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