SCHEMBL29640446

SCHEMBL29640446

CCCCCCCCc1ccc2c(c1)Nc1cc(CCCCCCCC)ccc1S2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.46
ESR1 P03372 2/20 0.46
ADRA2A P08913 2/20 0.46
ADORA3 P0DMS8 2/20 0.46
TACR2 P21452 2/20 0.46
SLC6A2 P23975 2/20 0.46
SLC6A4 P31645 2/20 0.46
SLC6A3 Q01959 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
SHBG P04278 1/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
HSPD1 P10809 1/20 0.46
ADRB3 P13945 1/20 0.46
HTR2C P28335 1/20 0.46
HSPE1 P61604 1/20 0.46
HIF1A Q16665 1/20 0.46
TST Q16762 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL227468 1.00 PTGS2 (0.46) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL7771194 1.00 PTGS2 (0.46) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL29640460 1.00 PTGS2 (0.46) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL7528258 0.92 NOX1 (0.50) PTGS2ADORA3SLC6A2SLC6A3ALDH1A1
SCHEMBL31366233 0.92 NOX1 (0.50) PTGS2ADORA3SLC6A2SLC6A3ALDH1A1
SCHEMBL17999681 0.92 NOX1 (0.50) PTGS2ADORA3SLC6A2SLC6A3ALDH1A1
SCHEMBL7773452 0.92 NOX1 (0.50) PTGS2ADORA3SLC6A2SLC6A3ALDH1A1
SCHEMBL17999668 0.91 NOX1 (0.52) PTGS2ADORA3SLC6A2SLC6A3ALDH1A1
SCHEMBL225844 0.86 PTGS2 (0.46) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL8142919 0.86 PTGS2 (0.46) PTGS2ESR1ADRA2AADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4055065-A2 COMPOSITION FOR IMMEDIATE TERMINATION OF FREE-RADICAL POLYMERIZATION AND USES THEREOF RHODIA OPERATIONS (FR) 2022-09-14 EP disclosed
CN-114641507-A Compositions for immediate termination of free radical polymerization and uses thereof 罗地亚经营管理公司 2022-06-17 CN disclosed