SCHEMBL29640516

SCHEMBL29640516

COc1cc(C)cc(OC=O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
CYP1A1 P04798 3/20 0.43
CYP1B1 Q16678 3/20 0.43
ACHE P22303 2/20 0.40
CYP3A4 P08684 3/20 0.37
ESR1 P03372 2/20 0.36
NQO2 P16083 2/20 0.36
CYP1A2 P05177 2/20 0.36
ABL1 P00519 1/20 0.36
TTR P02766 1/20 0.36
ABCB1 P08183 1/20 0.36
ALOX5 P09917 1/20 0.36
BCR P11274 1/20 0.36
CYP19A1 P11511 1/20 0.36
PTGS2 P35354 1/20 0.36
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
AHR P35869 1/20 0.36
TUBA1B P68363 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23457679 1.00 ALDH1A1 (0.48) ALDH1A1CYP1A1CYP1B1ACHECYP3A4
SCHEMBL16079851 0.91 ALDH1A1 (0.41) ALDH1A1ACHECYP3A4ERN1KDM4E
SCHEMBL2092735 0.91 ALDH1A1 (0.58) ALDH1A1CYP1A1CYP1B1CYP3A4ESR1
SCHEMBL1190708 0.86 ALDH1A1 (0.46) ALDH1A1CYP3A4ERN1MAPTHPGD
SCHEMBL21726722 0.81 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1ESR1NQO2
SCHEMBL12501 0.81 ALDH1A1 (0.73) ALDH1A1CYP1A1CYP1B1ACHECYP3A4
SCHEMBL18573171 0.78 ALDH1A1 (0.32) ALDH1A1
SCHEMBL27618726 0.78 ALDH1A1 (0.42) ALDH1A1CYP1A1CYP1B1NQO2TDP1
SCHEMBL8804437 0.77 ALDH1A1 (0.48) ALDH1A1CYP1A1CYP1B1ACHECYP3A4
SCHEMBL17898604 0.77 ALDH1A1 (0.50) ALDH1A1CYP3A4ERN1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4007748-A1 ENOL ETHER PROPERFUME Firmenich SA (CH) 2022-06-08 EP disclosed