SCHEMBL29640566

SCHEMBL29640566

Clc1ccc(CCC#Cc2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.57
FFAR4 Q5NUL3 3/20 0.57
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
THPO P40225 1/20 0.44
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
GRM5 P41594 1/20 0.41
HRH3 Q9Y5N1 2/20 0.41
KCNH2 Q12809 2/20 0.41
TAAR1 Q96RJ0 1/20 0.41
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
APP P05067 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5249356 0.86 FFAR1 (0.66) FFAR1FFAR4CYP1A2CYP3A4CYP2C9
SCHEMBL28772070 0.82 FFAR1 (0.50) FFAR1FFAR4CYP1A2CYP3A4CYP2C9
SCHEMBL28256625 0.76 FFAR1 (0.50) FFAR1FFAR4KCNH2ALDH1A1APP
SCHEMBL10768214 0.75 CYP1A2 (0.64) FFAR1FFAR4CYP1A2CYP3A4CYP2C9
SCHEMBL29187194 0.75 GRM5 (0.54) FFAR1FFAR4CYP1A2CYP3A4CYP2C9
SCHEMBL17743740 0.74 FFAR1 (0.61) FFAR1FFAR4CYP1A2CYP3A4CYP2C9
SCHEMBL10798421 0.74 FFAR1 (0.61) FFAR1FFAR4MEN1KMT2AGRM5
SCHEMBL28585298 0.73 FFAR1 (0.51) FFAR1FFAR4CYP1A2CYP3A4CYP2C9
SCHEMBL28476337 0.73 FFAR1 (0.51) FFAR1FFAR4CYP1A2CYP3A4CYP2C9
SCHEMBL16050106 0.73 FFAR1 (0.77) FFAR1FFAR4ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110256365-B Method for preparing benzodiazepine derivative by catalysis of dichlorotitanocene 陕西师范大学 2022-06-07 CN disclosed