Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.66 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29187194 | 0.87 | GRM5 (0.54) | FFAR1FFAR4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10798421 | 0.86 | FFAR1 (0.61) | FFAR1FFAR4GRM5SIGMAR1HRH3 | |
| SCHEMBL17743740 | 0.86 | FFAR1 (0.61) | FFAR1FFAR4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29640566 | 0.86 | FFAR1 (0.57) | FFAR1FFAR4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28585298 | 0.85 | FFAR1 (0.51) | FFAR1FFAR4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28476337 | 0.85 | FFAR1 (0.51) | FFAR1FFAR4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10768214 | 0.83 | CYP1A2 (0.64) | FFAR1FFAR4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9303814 | 0.83 | ALDH1A1 (0.52) | FFAR1FFAR4GRM5HTR2AALDH1A1 | |
| SCHEMBL3843357 | 0.80 | GRM5 (0.48) | FFAR1FFAR4GRM5HRH3DRD2 | |
| SCHEMBL16050106 | 0.80 | FFAR1 (0.77) | FFAR1FFAR4ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119977812-A | Method for synthesizing 1, 4-diphenyl-1-butyne derivatives by nickel catalytic reduction coupling | 华南理工大学 | 2025-05-13 | — | — | CN | claimed |
| EP-1476438-B1 | OXA- AND THIADIAZOLES AND THEIR USE AS METALLOPROTEINASE INHIBITORS | VERNALIS R&D LTD (GB) | 2007-04-18 | — | — | EP | claimed |
| CN-119977812-A | Method for synthesizing 1, 4-diphenyl-1-butyne derivatives by nickel catalytic reduction coupling | 华南理工大学 | 2025-05-13 | — | — | CN | disclosed |
| CN-119977812-A | Method for synthesizing 1, 4-diphenyl-1-butyne derivatives by nickel catalytic reduction coupling | 华南理工大学 | 2025-05-13 | — | — | CN | disclosed |
| CN-119977812-A | Method for synthesizing 1, 4-diphenyl-1-butyne derivatives by nickel catalytic reduction coupling | 华南理工大学 | 2025-05-13 | — | — | CN | disclosed |
| EP-1765795-A2 | ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Addex Pharmaceuticals SA (CH) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005123703-A2 | ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMACEUTICALS SA (CH) | 2005-12-29 | — | — | WO | disclosed |