Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL511950 | 1.00 | POLB (0.56) | POLBCTBP2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL4319346 | 0.88 | CTBP2 (0.51) | POLBCTBP2CYP1A2ALDH1A1KDM4E | |
| SCHEMBL30172792 | 0.88 | CTBP2 (0.51) | POLBCTBP2CYP1A2ALDH1A1KDM4E | |
| SCHEMBL28262488 | 0.88 | POLB (0.54) | POLBCTBP2L3MBTL1CYP1A2 | |
| SCHEMBL2008583 | 0.87 | PPARA (0.57) | L3MBTL1ALDH1A1KDM4EMAPTPPARG | |
| SCHEMBL31285834 | 0.87 | PPARA (0.57) | L3MBTL1ALDH1A1KDM4EMAPTPPARG | |
| SCHEMBL68412 | 0.86 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1MAPTPPARGPPARA | |
| SCHEMBL2096727 | 0.86 | PPARA (0.49) | POLBCTBP2L3MBTL1ALDH1A1PPARG | |
| SCHEMBL21540041 | 0.85 | L3MBTL1 (0.53) | POLBCTBP2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL4128970 | 0.85 | PPARA (0.52) | POLBCTBP2L3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218857-B | P300/CBP HAT inhibitors and methods of use thereof | 星座制药公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114450005-A | Compounds for the treatment of neurological disorders | 星座制药公司 | 2022-05-06 | — | — | CN | disclosed |