SCHEMBL29641093

SCHEMBL29641093

N=C(N)NCCC[C@@H](N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ C5AR1 P21730 2/20 0.64
▸ MC4R P32245 1/20 0.55
▸ APLNR P35414 2/20 0.53
▸ OPRM1 P35372 5/20 0.53
▸ OPRD1 P41143 2/20 0.53
▸ F2 P00734 1/20 0.52
▸ OPRK1 P41145 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29641118 0.94 C5AR1 (0.60) C5AR1MC4RAPLNROPRM1OPRD1
SCHEMBL30974009 0.92 C5AR1 (0.62) C5AR1APLNROPRM1OPRD1F2
SCHEMBL30974277 0.92 C5AR1 (0.62) C5AR1APLNROPRM1F2OPRK1
SCHEMBL29976469 0.91 C5AR1 (0.65) C5AR1APLNROPRM1OPRD1
SCHEMBL29619803 0.91 C5AR1 (0.65) C5AR1APLNROPRM1OPRD1
SCHEMBL29569062 0.91 C5AR1 (0.65) C5AR1APLNROPRM1OPRD1OPRK1
SCHEMBL31127566 0.89 OPRM1 (0.60) C5AR1OPRM1OPRD1F2
SCHEMBL29607931 0.89 C5AR1 (0.55) C5AR1MC4RAPLNROPRM1OPRK1
SCHEMBL29701253 0.89 C5AR1 (0.64) C5AR1APLNROPRM1OPRD1
SCHEMBL31574325 0.89 C5AR1 (0.68) C5AR1APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4596049-A2 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2025-08-06 — — EP disclosed
EP-4302829-B1 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION STEALTH BIOTHERAPEUTICS INC (US) 2025-05-21 — — EP disclosed
EP-3603658-B1 PEPTIDE FOR USE IN THE TREATMENT OF HEART FAILURE RESULTING FROM HYPERTROPHIC CARDIOMYOPATHY UNIV CORNELL (US) 2025-01-08 — — EP disclosed
EP-4302829-A2 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2024-01-10 — — EP disclosed
EP-3708178-B1 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION STEALTH BIOTHERAPEUTICS INC (US) 2023-10-04 — — EP disclosed
EP-4233887-A1 METHODS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY Stealth BioTherapeutics Inc. (US) 2023-08-30 — — EP disclosed
US-20230109564-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY STEALTH BIOTHERAPEUTICS INC. (US) 2023-04-06 — — US disclosed
EP-3513800-B1 AROMATIC-CATIONIC PEPTIDE FOR USE IN THE TREATMENT OF ANTIPHOSPHOLIPID SYNDROME UNIV CORNELL (US) 2022-12-07 — — EP disclosed
EP-4085920-A1 METHODS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY Stealth BioTherapeutics Inc. (US) 2022-11-09 — — EP disclosed
EP-4000690-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MITOCHONDRIAL MYOPATHIES Stealth BioTherapeutics Inc. (US) 2022-05-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230109564-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY MTPN, UTRN, SMN1; SMN2 C5AR1 1000/4885MC4R 2331/4885APLNR 393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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