Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16765225 | 1.00 | SIGMAR1 (0.39) | SIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL16765223 | 1.00 | SIGMAR1 (0.39) | SIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL21618463 | 0.76 | MAPT (0.43) | SIGMAR1 | |
| SCHEMBL29638005 | 0.76 | SIGMAR1 (0.48) | SIGMAR1 | |
| SCHEMBL29641252 | 0.75 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL16764655 | 0.75 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL16764657 | 0.75 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL15139270 | 0.72 | FUCA1 (0.50) | SIGMAR1 | |
| SCHEMBL21622343 | 0.72 | FUCA1 (0.50) | SIGMAR1 | |
| SCHEMBL15139268 | 0.72 | FUCA1 (0.50) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551862-B | Macrocyclic inhibitors of peptidyl arginine deiminase | 吉利德科学公司 | 2024-04-12 | — | — | CN | disclosed |
| EP-4267562-A1 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2023-11-01 | — | — | EP | disclosed |
| EP-4267587-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | Gilead Sciences, Inc. (US) | 2023-11-01 | — | — | EP | disclosed |
| CN-115551862-A | Macrocyclic inhibitors of peptidyl arginine deiminase | 吉利德科学公司 | 2022-12-30 | — | — | CN | disclosed |
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |
| WO-2022140390-A1 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |