Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 2/20 | 0.48 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.43 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721845 | 1.00 | IL2 (0.48) | IL2STIM1ORAI1ORAI2LMNA | |
| SCHEMBL29642130 | 0.88 | IL2 (0.61) | IL2STIM1ORAI1ORAI2SMN1; SMN2 | |
| SCHEMBL723614 | 0.88 | IL2 (0.61) | IL2STIM1ORAI1ORAI2SMN1; SMN2 | |
| SCHEMBL10201327 | 0.83 | STIM1 (0.48) | STIM1ORAI1ORAI2LMNAMAPT | |
| SCHEMBL10201081 | 0.82 | STIM1 (0.54) | STIM1ORAI1ORAI2LMNAMAPT | |
| SCHEMBL14881301 | 0.81 | MEN1 (0.53) | IL2STIM1ORAI1LMNAMAPT | |
| SCHEMBL14881367 | 0.80 | MAPT (0.53) | LMNAMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL1701611 | 0.79 | STIM1 (0.65) | IL2STIM1ORAI1ORAI2LMNA | |
| SCHEMBL1701825 | 0.78 | STIM1 (0.62) | IL2STIM1ORAI1ORAI2SMN1; SMN2 | |
| SCHEMBL766985 | 0.76 | STIM1 (0.47) | STIM1ORAI1ORAI2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591311-A | Compounds that modulate intracellular calcium | 钙医学公司 | 2022-06-07 | — | — | CN | disclosed |