Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 6/20 | 0.61 |
| ▸ | STIM1 | Q13586 | 5/20 | 0.52 |
| ▸ | ORAI1 | Q96D31 | 5/20 | 0.52 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723614 | 1.00 | IL2 (0.61) | IL2STIM1ORAI1ORAI2SCN9A | |
| SCHEMBL29642090 | 0.88 | IL2 (0.48) | IL2STIM1ORAI1ORAI2SCN9A | |
| SCHEMBL721845 | 0.88 | IL2 (0.48) | IL2STIM1ORAI1ORAI2SCN9A | |
| SCHEMBL10201325 | 0.83 | STIM1 (0.58) | IL2STIM1ORAI1ORAI2GAA | |
| SCHEMBL10201079 | 0.82 | STIM1 (0.65) | IL2STIM1ORAI1ORAI2GAA | |
| SCHEMBL29642101 | 0.82 | STIM1 (0.65) | IL2STIM1ORAI1ORAI2GAA | |
| SCHEMBL14887381 | 0.80 | IL2 (0.56) | IL2STIM1ORAI1ORAI2SCN9A | |
| SCHEMBL14881425 | 0.79 | STIM1 (0.51) | IL2STIM1ORAI1ORAI2MEN1 | |
| SCHEMBL1702182 | 0.79 | STIM1 (0.77) | IL2STIM1ORAI1ORAI2MEN1 | |
| SCHEMBL14158774 | 0.78 | STIM1 (0.61) | IL2STIM1ORAI1ORAI2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591311-A | Compounds that modulate intracellular calcium | 钙医学公司 | 2022-06-07 | — | — | CN | disclosed |