Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 4/20 | 0.71 |
| ▸ | ORAI1 | Q96D31 | 4/20 | 0.71 |
| ▸ | IL2 | P60568 | 2/20 | 0.59 |
| ▸ | ESRRG | P62508 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721821 | 1.00 | STIM1 (0.71) | STIM1ORAI1IL2ESRRGNPC1 | |
| SCHEMBL10201105 | 0.89 | STIM1 (0.83) | STIM1ORAI1IL2ESRRGNPC1 | |
| SCHEMBL720496 | 0.86 | STIM1 (0.64) | STIM1ORAI1IL2ESRRGNPC1 | |
| SCHEMBL721455 | 0.83 | STIM1 (1.00) | STIM1ORAI1IL2ESRRGNPC1 | |
| SCHEMBL10201122 | 0.78 | IL2 (0.57) | STIM1ORAI1IL2ESRRGMEN1 | |
| SCHEMBL29642097 | 0.78 | IL2 (0.57) | STIM1ORAI1IL2ESRRGMEN1 | |
| SCHEMBL10201083 | 0.77 | STIM1 (0.75) | STIM1ORAI1NPC1RAB9AMEN1 | |
| SCHEMBL720890 | 0.75 | STIM1 (0.62) | STIM1ORAI1IL2ESRRGNPC1 | |
| SCHEMBL8262127 | 0.74 | IL2 (1.00) | STIM1ORAI1IL2ESRRGTP53 | |
| SCHEMBL5267400 | 0.73 | IL2 (0.76) | STIM1ORAI1IL2ESRRGNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591311-A | Compounds that modulate intracellular calcium | 钙医学公司 | 2022-06-07 | — | — | CN | disclosed |