Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 5/20 | 0.65 |
| ▸ | ORAI1 | Q96D31 | 5/20 | 0.65 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | IL2 | P60568 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10201079 | 1.00 | STIM1 (0.65) | STIM1ORAI1ORAI2MEN1KMT2A | |
| SCHEMBL10201675 | 0.91 | STIM1 (0.53) | STIM1ORAI1ORAI2MEN1KMT2A | |
| SCHEMBL29642084 | 0.91 | STIM1 (0.53) | STIM1ORAI1ORAI2MEN1KMT2A | |
| SCHEMBL10201081 | 0.89 | STIM1 (0.54) | STIM1ORAI1ORAI2MEN1KMT2A | |
| SCHEMBL10201676 | 0.83 | STIM1 (0.46) | STIM1ORAI1ORAI2MEN1KMT2A | |
| SCHEMBL10201325 | 0.82 | STIM1 (0.58) | STIM1ORAI1ORAI2LMNAIL2 | |
| SCHEMBL723614 | 0.82 | IL2 (0.61) | STIM1ORAI1ORAI2MEN1KMT2A | |
| SCHEMBL29642130 | 0.82 | IL2 (0.61) | STIM1ORAI1ORAI2MEN1KMT2A | |
| SCHEMBL1701956 | 0.81 | STIM1 (0.66) | STIM1ORAI1ORAI2MEN1KMT2A | |
| SCHEMBL1702182 | 0.80 | STIM1 (0.77) | STIM1ORAI1ORAI2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591311-A | Compounds that modulate intracellular calcium | 钙医学公司 | 2022-06-07 | — | — | CN | disclosed |