Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.62 |
| ▸ | STIM1 | Q13586 | 4/20 | 0.57 |
| ▸ | ORAI1 | Q96D31 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10201084 | 1.00 | PDE10A (0.62) | PDE10ASTIM1ORAI1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10201476 | 0.85 | STIM1 (0.59) | PDE10ASTIM1ORAI1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10201077 | 0.82 | PDE10A (0.51) | PDE10ASTIM1ORAI1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10201197 | 0.82 | LMNA (0.46) | PDE10ASMN1; SMN2ALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL10201059 | 0.78 | STIM1 (0.79) | PDE10ASTIM1ORAI1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10263079 | 0.77 | STIM1 (0.57) | PDE10ASTIM1ORAI1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10201043 | 0.77 | STIM1 (0.57) | PDE10ASTIM1ORAI1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10201033 | 0.77 | STIM1 (0.78) | PDE10ASTIM1ORAI1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10201049 | 0.76 | STIM1 (0.76) | PDE10ASTIM1ORAI1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10201055 | 0.75 | STIM1 (0.86) | PDE10ASTIM1ORAI1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591311-A | Compounds that modulate intracellular calcium | 钙医学公司 | 2022-06-07 | — | — | CN | disclosed |