Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.78 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.78 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.78 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.78 |
| ▸ | MRGPRX2 | Q96LB1 | 5/20 | 0.76 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.76 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.76 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.76 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20306854 | 1.00 | OPRM1 (0.78) | OPRM1OPRK1OPRD1SIGMAR1MRGPRX2 | |
| SCHEMBL46251 | 1.00 | OPRM1 (0.78) | OPRM1OPRK1OPRD1SIGMAR1MRGPRX2 | |
| SCHEMBL20348444 | 1.00 | OPRM1 (0.78) | OPRM1OPRK1OPRD1SIGMAR1MRGPRX2 | |
| SCHEMBL10045461 | 0.89 | OPRM1 (0.81) | OPRM1OPRK1OPRD1SIGMAR1MRGPRX2 | |
| SCHEMBL12030889 | 0.89 | OPRM1 (0.81) | OPRM1OPRK1OPRD1SIGMAR1MRGPRX2 | |
| Nalorphine SCHEMBL12091243 | 0.88 | OPRM1 (1.00) | OPRM1OPRK1OPRD1SIGMAR1MRGPRX2 | |
| Nalorphine SCHEMBL19199030 | 0.88 | OPRM1 (1.00) | OPRM1OPRK1OPRD1SIGMAR1MRGPRX2 | |
| Nalorphine SCHEMBL16015635 | 0.88 | OPRM1 (1.00) | OPRM1OPRK1OPRD1SIGMAR1MRGPRX2 | |
| Nalorphine SCHEMBL38920 | 0.88 | OPRM1 (1.00) | OPRM1OPRK1OPRD1SIGMAR1MRGPRX2 | |
| Nalorphine SCHEMBL12230555 | 0.88 | OPRM1 (1.00) | OPRM1OPRK1OPRD1SIGMAR1MRGPRX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023044086-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CANCERS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-03-23 | — | — | WO | disclosed |
| EP-3990679-A1 | APPARATUS FOR FORMING A PLURALITY OF COATED PARTICLES, METHOD FOR FORMING A PLURALITY OF COATED PARTICLES, COATED PARTICLES | Nanexa AB (SE) | 2022-05-04 | — | — | EP | disclosed |