SCHEMBL29643180

SCHEMBL29643180

OB(O)c1c2ccccc2c(-c2ccc(-c3cccc4ccccc34)cc2)c2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
CA12 O43570 3/20 0.44
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA9 Q16790 3/20 0.44
PPARG P37231 9/20 0.41
PPARA Q07869 9/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
PPARD Q03181 1/20 0.41
MCL1 Q07820 1/20 0.41
ACMSD Q8TDX5 1/20 0.41
ENPP3 O14638 1/20 0.41
ENPP1 P22413 1/20 0.41
CYP1A2 P05177 1/20 0.40
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA7 P36544 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1527523 1.00 HDAC8 (0.46) HDAC8HDAC6CA12CA1CA2
SCHEMBL1527580 0.87 MCL1 (0.42) HDAC8HDAC6CA12CA1CA2
SCHEMBL30100455 0.87 MCL1 (0.42) HDAC8HDAC6CA12CA1CA2
SCHEMBL971636 0.86 DHFR (0.40) HDAC8HDAC6MCL1ACMSDCYP1A2
SCHEMBL29464271 0.86 DHFR (0.40) HDAC8HDAC6MCL1ACMSDCYP1A2
SCHEMBL24446252 0.86 CA12 (0.55) HDAC8HDAC6CA12CA1CA2
SCHEMBL29995332 0.82 TNF (0.52) HDAC8HDAC6CA12CA1CA2
SCHEMBL16105349 0.82 TNF (0.52) HDAC8HDAC6CA12CA1CA2
SCHEMBL3925327 0.82 CA12 (0.51) HDAC8HDAC6CA12CA1CA2
SCHEMBL2252435 0.81 HDAC8 (0.50) HDAC8HDAC6CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120077329-A Photosensitive resin composition, photosensitive resin laminate, and method for forming resist pattern 旭化成株式会社 2025-05-30 CN disclosed
WO-2024085254-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN MULTILAYER BODY, AND METHOD FOR FORMING RESIST PATTERN 旭化成株式会社 2024-04-25 WO disclosed
US-11456421-B2 Anthracene derivatives, luminescent materials and organic electroluminescent devices IDEMITSU KOSAN CO., LTD. (JP) 2022-09-27 US disclosed
CN-114524762-A Blue light host material based on spiroindole and anthracene and application thereof in organic electroluminescent device 上海传勤新材料有限公司 2022-05-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11456421-B2 Anthracene derivatives, luminescent materials and organic electroluminescent devices ANXA7, AAAS, ANXA1 HDAC8 1321/4885HDAC6 3500/4885CA12 1330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.