Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13472308 | 1.00 | NPC1 (0.44) | NPC1MAPTALDH1A1TP53XBP1 | |
| SCHEMBL13472307 | 0.85 | KDM5B (0.48) | NPC1MAPTALDH1A1TP53XBP1 | |
| SCHEMBL2258738 | 0.83 | CA12 (0.42) | NPC1MAPTALDH1A1TP53XBP1 | |
| SCHEMBL13472446 | 0.82 | MAPT (0.43) | NPC1MAPTALDH1A1TP53XBP1 | |
| SCHEMBL22118282 | 0.82 | NPC1 (0.43) | NPC1MAPTALDH1A1TP53XBP1 | |
| SCHEMBL18703831 | 0.81 | NPC1 (0.43) | NPC1MAPTALDH1A1TP53XBP1 | |
| SCHEMBL10177616 | 0.80 | GABRA1 (0.42) | NPC1MAPTALDH1A1TP53XBP1 | |
| SCHEMBL716161 | 0.80 | MAPT (0.41) | NPC1MAPTALDH1A1TP53XBP1 | |
| SCHEMBL13474037 | 0.78 | HPGD (0.44) | NPC1MAPTALDH1A1TP53XBP1 | |
| SCHEMBL2743308 | 0.78 | NPC1 (0.46) | NPC1MAPTALDH1A1TP53XBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255911-A1 | BICYCLIC DERIVATIVES | Elanco Tiergesundheit AG (CH) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022117783-A1 | BICYCLIC DERIVATIVES | ELANCO TIERGESUNDHEIT AG (CH) | 2022-06-09 | — | — | WO | disclosed |