Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL2953429 | 0.98 | TDP1 (0.44) | TDP1 | |
| Succinic Acid SCHEMBL2955156 | 0.97 | TDP1 (0.40) | TDP1 | |
| Adipic Acid SCHEMBL2949814 | 0.94 | TDP1 (0.42) | TDP1 | |
| Adipic Acid SCHEMBL2956608 | 0.93 | TDP1 (0.41) | TDP1 | |
| Adipic Acid SCHEMBL2954237 | 0.91 | TDP1 (0.38) | TDP1 | |
| Succinic Acid SCHEMBL28693360 | 0.89 | TDP1 (0.43) | TDP1 | |
| Succinic Acid SCHEMBL29008437 | 0.88 | TDP1 (0.41) | TDP1 | |
| Cadaverine Tartrate SCHEMBL2961686 | 0.88 | TDP1 (0.45) | TDP1 | |
| Succinic Acid SCHEMBL2952946 | 0.88 | TDP1 (0.49) | TDP1 | |
| Cadaverine Tartrate SCHEMBL2957400 | 0.86 | TDP1 (0.44) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7766978-B2 | Acidic hair dyeing method | KOKYU ALCOHOL KOGYO CO., LTD. (JP) | 2010-08-03 | — | — | US | disclosed |
| US-20090100609-A1 | ACIDIC HAIR DYE COMPOSITION | KOKYU ALCOHOL KOGYO CO., LTD. (JP) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090100609-A1 | ACIDIC HAIR DYE COMPOSITION | H1-0, MRM1, H1-4 | TDP1 1628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.