Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.76 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GPR3 | P46089 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21775981 | 0.93 | KDM4E (0.64) | KDM4ENPC1ALDH1A1HSD17B10BRD4 | |
| SCHEMBL28039676 | 0.90 | KDM4E (0.62) | KDM4ENPC1ALDH1A1HSD17B10BRD4 | |
| SCHEMBL30850787 | 0.86 | KDM4E (1.00) | KDM4ENPC1ALDH1A1HSD17B10GPR3 | |
| SCHEMBL2026269 | 0.86 | KDM4E (0.76) | KDM4ENPC1ALDH1A1HSD17B10GPR3 | |
| SCHEMBL3102894 | 0.86 | KDM4E (1.00) | KDM4ENPC1ALDH1A1HSD17B10GPR3 | |
| SCHEMBL23863969 | 0.85 | KDM4E (0.64) | KDM4ENPC1ALDH1A1HSD17B10GPR3 | |
| SCHEMBL29643244 | 0.83 | NPC1 (0.80) | KDM4ENPC1ALDH1A1HPGDMAPT | |
| SCHEMBL28266234 | 0.83 | NPC1 (0.80) | KDM4ENPC1ALDH1A1HPGDMAPT | |
| SCHEMBL4687866 | 0.82 | KDM4E (0.69) | KDM4ENPC1ALDH1A1HSD17B10GPR3 | |
| SCHEMBL9760859 | 0.82 | KDM4E (0.69) | KDM4ENPC1ALDH1A1HSD17B10GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206360-B | Carbazole amide derivative or salt thereof, and preparation method and application thereof | 复旦大学 | 2022-05-17 | — | — | CN | disclosed |