SCHEMBL29643238

SCHEMBL29643238

Cc1cccc2c3ccccc3n(C3CC3)c12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.56
FTO Q9C0B1 1/20 0.56
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
C5AR1 P21730 3/20 0.36
DDB1 Q16531 2/20 0.36
CRBN Q96SW2 2/20 0.36
GPR3 P46089 1/20 0.36
CYP1A2 P05177 2/20 0.35
CYP2A6 P11509 2/20 0.35
CYP2C19 P33261 1/20 0.35
PRKD3 O94806 1/20 0.35
PRKCG P05129 1/20 0.35
PRKCB P05771 1/20 0.35
PRKCA P17252 1/20 0.35
PRKCH P24723 1/20 0.35
PRKCI P41743 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29643421 0.92 ALKBH5 (0.51) ALKBH5FTOKDM4EALDH1A1MEN1
SCHEMBL17349109 0.92 ALKBH5 (0.51) ALKBH5FTOKDM4EALDH1A1MEN1
SCHEMBL31469417 0.79 CYP1A2 (0.48) KDM4EMAPTALDH1A1MEN1KMT2A
SCHEMBL22086475 0.74 ALKBH5 (0.50) ALKBH5FTOKDM4EMAPTALDH1A1
SCHEMBL17147710 0.72 ALKBH5 (0.66) ALKBH5FTOKDM4EMAPTALDH1A1
SCHEMBL146377 0.72 ALKBH5 (1.00) ALKBH5FTOKDM4EMAPTALDH1A1
SCHEMBL524763 0.71 MEN1 (0.50) KDM4EALDH1A1MEN1KMT2ADDB1
SCHEMBL31469456 0.71 MEN1 (0.50) KDM4EALDH1A1MEN1KMT2ADDB1
SCHEMBL31469424 0.71 MEN1 (0.50) KDM4EALDH1A1MEN1KMT2ADDB1
SCHEMBL30417189 0.71 MEN1 (0.50) KDM4EALDH1A1MEN1KMT2ADDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109206360-B Carbazole amide derivative or salt thereof, and preparation method and application thereof 复旦大学 2022-05-17 CN disclosed