Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | HBB | P68871 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 8/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10163400 | 0.86 | KDM4E (0.66) | KDM4ELMNAMAPK1POLBMAPT | |
| SCHEMBL12158838 | 0.86 | KDM4E (0.66) | KDM4ELMNAMAPK1POLBMAPT | |
| SCHEMBL30523147 | 0.86 | KDM4E (0.58) | KDM4ELMNAMAPK1POLBMAPT | |
| SCHEMBL27275930 | 0.85 | MAPT (0.68) | KDM4ELMNAMAPK1POLBMAPT | |
| SCHEMBL23318411 | 0.84 | KDM4E (0.59) | KDM4ELMNAMAPK1POLBMAPT | |
| SCHEMBL29643289 | 0.84 | KDM4E (0.59) | KDM4ELMNAMAPK1POLBMAPT | |
| SCHEMBL2852617 | 0.83 | KDM4E (0.67) | KDM4ELMNAMAPK1POLBMAPT | |
| SCHEMBL2600216 | 0.83 | KDM4E (0.62) | KDM4ELMNAMAPK1POLBMAPT | |
| SCHEMBL4849333 | 0.83 | KDM4E (0.67) | KDM4ELMNAMAPK1POLBMAPT | |
| SCHEMBL30523156 | 0.83 | KDM4E (0.56) | KDM4ELMNAMAPK1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206360-B | Carbazole amide derivative or salt thereof, and preparation method and application thereof | 复旦大学 | 2022-05-17 | — | — | CN | disclosed |