Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | HBB | P68871 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 8/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5163862 | 0.91 | KDM4E (0.64) | KDM4ELMNAMAPK1POLBMAPT | |
| SCHEMBL5794326 | 0.87 | KDM4E (0.63) | KDM4ELMNAMAPK1POLBMAPT | |
| SCHEMBL5807330 | 0.87 | PGR (0.63) | KDM4ELMNAMAPK1POLBMAPT | |
| SCHEMBL12158838 | 0.86 | KDM4E (0.66) | KDM4ELMNAMAPK1POLBMAPT | |
| SCHEMBL10163400 | 0.86 | KDM4E (0.66) | KDM4ELMNAMAPK1POLBMAPT | |
| SCHEMBL27275930 | 0.85 | MAPT (0.68) | KDM4ELMNAMAPK1POLBMAPT | |
| SCHEMBL2852617 | 0.83 | KDM4E (0.67) | KDM4ELMNAMAPK1POLBMAPT | |
| SCHEMBL2600216 | 0.83 | KDM4E (0.62) | KDM4ELMNAMAPK1POLBMAPT | |
| SCHEMBL29643256 | 0.83 | KDM4E (0.62) | KDM4ELMNAMAPK1POLBMAPT | |
| SCHEMBL5794680 | 0.83 | KDM4E (0.55) | KDM4ELMNAMAPK1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003089-B | 3-hydroxymethyl-9-substituted carbazole and preparation method thereof | 陕西科技大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-110759852-A | Preparation method of 3-hydroxymethyl-9-substituted carbazole | 陕西科技大学 | 2020-02-07 | — | — | CN | disclosed |
| CN-110003089-A | A kind of 3- methylol -9- substituted carbazole and preparation method thereof | 陕西科技大学 | 2019-07-12 | — | — | CN | disclosed |
| US-7348116-B2 | Aromatic heterocyclic-based charge transport materials having two amino groups | SAMSUNG ELECTRONICS, LTD (KR) | 2008-03-25 | — | — | US | disclosed |
| US-20060051690-A1 | Aromatic heterocyclic-based charge transport materials having two amino groups | S-PRINTING SOLUTION CO., LTD. (KR) | 2006-03-09 | — | — | US | disclosed |
| WO-2006012310-A2 | CARBAZOLE DERIVATIVES FOR TREATING POLYCYSTIC KIDNEY DISEASE | GENZYME CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |
| US-6878468-B2 | Compounds capable of transporting/injecting hole and organic electroluminescent device having self-assembled monolayer comprising the same | ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) | 2005-04-12 | — | — | US | disclosed |
| US-20030087127-A1 | Compounds capable of transporting/injecting hole and organic electroluminescent device having self-assembled monolayer comprising the same | ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) | 2003-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087127-A1 | Compounds capable of transporting/injecting hole and organic electroluminescent device having self-assembled monolayer comprising the same | SLCO4C1, SLC26A3, SLCO2B1 | KDM4E 4413/4885LMNA 1670/4885MAPK1 1345/4885 |
| US-20060051690-A1 | Aromatic heterocyclic-based charge transport materials having two amino groups | SLC43A1, SLC6A19, SLC1A2 | KDM4E 2167/4885LMNA 2532/4885MAPK1 2360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.