Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20702366 | 0.86 | KMT2A (0.47) | KMT2AMEN1NPC1RAB9AATM | |
| SCHEMBL20138823 | 0.78 | KMT2A (0.51) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL20154246 | 0.78 | PDE4B (0.51) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL30071172 | 0.78 | PDE4B (0.51) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL3061001 | 0.77 | KMT2A (0.50) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL6293263 | 0.76 | KMT2A (0.68) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL437697 | 0.76 | KMT2A (0.68) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL20714623 | 0.76 | MMP1 (0.46) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL30071070 | 0.75 | KMT2A (0.48) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL20154238 | 0.75 | KMT2A (0.48) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255911-A1 | BICYCLIC DERIVATIVES | Elanco Tiergesundheit AG (CH) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022117783-A1 | BICYCLIC DERIVATIVES | ELANCO TIERGESUNDHEIT AG (CH) | 2022-06-09 | — | — | WO | disclosed |