Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.44 |
| ▸ | GALR2 | O43603 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031368 | 1.00 | MAPT (0.59) | MAPTNPSR1HTTKMT2APOLB | |
| SCHEMBL1634473 | 0.88 | NPSR1 (0.49) | MAPTNPSR1HTTKMT2APOLB | |
| SCHEMBL14676672 | 0.81 | HCAR3 (0.54) | MAPTHTTKMT2APOLBALDH3A1 | |
| SCHEMBL571816 | 0.80 | MAPT (0.64) | MAPTNPSR1HTTKMT2APOLB | |
| SCHEMBL30585155 | 0.80 | MAPT (0.64) | MAPTNPSR1HTTKMT2APOLB | |
| SCHEMBL2282371 | 0.80 | MAPT (0.68) | MAPTNPSR1HTTKMT2APOLB | |
| SCHEMBL12426042 | 0.78 | HTT (0.82) | MAPTNPSR1HTTKMT2APOLB | |
| SCHEMBL29657482 | 0.78 | MAPT (0.66) | MAPTNPSR1HTTKMT2APOLB | |
| SCHEMBL4835079 | 0.78 | MAPT (0.66) | MAPTNPSR1HTTKMT2APOLB | |
| SCHEMBL1532370 | 0.78 | MAPT (0.66) | MAPTNPSR1HTTKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115025086-A | Bicyclic heteroaryl derivatives, their preparation and use | 凯瑞康宁生物工程（武汉）有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-110709386-B | Bicyclic heteroaryl derivatives, their preparation and use | 凯瑞康宁生物工程（武汉）有限公司 | 2022-06-07 | — | — | CN | disclosed |