Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27140774 | 1.00 | AXL (0.34) | AXLCHUKMAPK1 | |
| SCHEMBL29643720 | 0.69 | CHUK (0.41) | CHUK | |
| SCHEMBL27149746 | 0.69 | CHUK (0.41) | CHUK | |
| SCHEMBL30204138 | 0.68 | AXL (0.44) | AXLCHUKMAPK1 | |
| SCHEMBL21178475 | 0.68 | AXL (0.44) | AXLCHUKMAPK1 | |
| SCHEMBL24005847 | 0.68 | RIPK1 (0.43) | AXL | |
| SCHEMBL26096528 | 0.68 | CHUK (0.43) | CHUK | |
| SCHEMBL19932698 | 0.66 | CHUK (0.38) | CHUK | |
| SCHEMBL19932697 | 0.66 | CHUK (0.38) | CHUK | |
| SCHEMBL14635390 | 0.65 | ADORA2A (0.50) | AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255904-A2 | NOVEL PAR-2 INHIBITORS | Domain Therapeutics (FR) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022117882-A2 | NOVEL PAR-2 INHIBITORS | DOMAIN THERAPEUTICS (FR) | 2022-06-09 | — | — | WO | disclosed |