Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.50 |
| ▸ | BRD2 | P25440 | 10/20 | 0.50 |
| ▸ | BRD3 | Q15059 | 8/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22524603 | 0.92 | BRD4 (0.48) | BRD4BRD2BRD3CREBBP | |
| SCHEMBL22524601 | 0.88 | BRD4 (0.46) | BRD4BRD2BRD3CREBBP | |
| SCHEMBL22524491 | 0.88 | BRD4 (0.45) | BRD4BRD2BRD3CREBBP | |
| SCHEMBL22524618 | 0.86 | BRD4 (0.51) | BRD4BRD2BRD3CREBBP | |
| SCHEMBL24244428 | 0.86 | LMNA (0.45) | BRD4BRD2BRD3CREBBP | |
| SCHEMBL22524612 | 0.85 | BRD4 (0.50) | BRD4BRD2BRD3CREBBP | |
| SCHEMBL22524558 | 0.84 | BRD4 (0.42) | BRD4BRD2BRD3CREBBP | |
| SCHEMBL22524532 | 0.84 | BRD4 (0.42) | BRD4BRD2BRD3CREBBP | |
| SCHEMBL22497657 | 0.84 | BRD4 (0.42) | BRD4BRD2BRD3CREBBP | |
| SCHEMBL22524494 | 0.84 | BRD4 (0.49) | BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177459-A1 | AROMATIC AMINE COMPOUND AND USE THEREOF IN PREPARATION OF AR AND BRD4 DUAL INHIBITORS AND REGULATORS | HINOVA PHARMACEUTICALS INC. (CN) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177459-A1 | AROMATIC AMINE COMPOUND AND USE THEREOF IN PREPARATION OF AR AND BRD4 DUAL INHIBITORS AND REGULATORS | AR, BRD4, BICRA | BRD4 2/4885BRD2 11/4885BRD3 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.