SCHEMBL29644449

SCHEMBL29644449

C[C@@H](CCO)CC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
ALOX15 P16050 1/20 0.39
TRPA1 O75762 1/20 0.34
DPP4 P27487 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21394 1.00 ALDH1A1 (0.39) ALDH1A1ALOX15TRPA1DPP4TSHR
SCHEMBL5310501 1.00 ALDH1A1 (0.39) ALDH1A1ALOX15TRPA1DPP4TSHR
SCHEMBL20446669 1.00 ALDH1A1 (0.39) ALDH1A1ALOX15TRPA1DPP4TSHR
SCHEMBL27982478 0.97 ALDH1A1 (0.38) ALDH1A1ALOX15TRPA1DPP4TSHR
Hydrochloric Acid SCHEMBL8820910 0.97 ALDH1A1 (0.38) ALDH1A1ALOX15TRPA1DPP4TSHR
SCHEMBL15477168 0.95 ALDH1A1 (0.41) ALDH1A1ALOX15TRPA1
Alcohol SCHEMBL15416777 0.95 ALDH1A1 (0.37) ALDH1A1ALOX15TRPA1TSHR
SCHEMBL16752544 0.91 ALDH1A1 (0.34) ALDH1A1ALOX15TRPA1DPP4
SCHEMBL16752545 0.91 ALDH1A1 (0.34) ALDH1A1ALOX15TRPA1DPP4
SCHEMBL28163734 0.85 ALDH1A1 (0.39) ALDH1A1ALOX15TRPA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114527209-A Marker combination for prognosis evaluation of liver cirrhosis 中国人民解放军总医院第五医学中心 2022-05-24 CN disclosed