Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dodecane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | CES2 | O00748 | 4/20 | 0.52 |
| ▸ | CES1 | P23141 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARD | Q03181 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL27389558 | 1.00 | ALDH1A1 (0.62) | ALDH1A1CES2CES1TSHRTHRB | |
| Heptane SCHEMBL27401561 | 1.00 | ALDH1A1 (0.62) | ALDH1A1CES2CES1TSHRTHRB | |
| Decane SCHEMBL15053043 | 1.00 | ALDH1A1 (0.62) | ALDH1A1CES2CES1TSHRTHRB | |
| Nonane SCHEMBL27883833 | 1.00 | ALDH1A1 (0.62) | ALDH1A1CES2CES1TSHRTHRB | |
| Hexadecane SCHEMBL380459 | 1.00 | ALDH1A1 (0.62) | ALDH1A1CES2CES1TSHRTHRB | |
| Octane SCHEMBL8954452 | 1.00 | ALDH1A1 (0.62) | ALDH1A1CES2CES1TSHRTHRB | |
| Octane SCHEMBL9793297 | 1.00 | ALDH1A1 (0.62) | ALDH1A1CES2CES1TSHRTHRB | |
| Nitric Acid SCHEMBL27586906 | 0.97 | ALDH1A1 (0.59) | ALDH1A1CES2CES1TSHRTHRB | |
| Heptane SCHEMBL27357041 | 0.97 | ALDH1A1 (0.59) | ALDH1A1CES2CES1TSHRTHRB | |
| Hexane SCHEMBL27687689 | 0.97 | ALDH1A1 (0.57) | ALDH1A1CES2CES1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12319654-B2 | Inert nanocapsules | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2025-06-03 | — | — | US | disclosed |
| US-20220177431-A1 | INERT NANOCAPSULES | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12319654-B2 | Inert nanocapsules | CHRM2, CHRM5, NCL | ALDH1A1 4254/4885CES2 1957/4885CES1 4328/4885 |
| US-20220177431-A1 | INERT NANOCAPSULES | CHRM2, CHRM5, CLN6 | ALDH1A1 4216/4885CES2 1894/4885CES1 4287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.