Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.68 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.66 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.66 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.57 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22276734 | 0.89 | LOXL2 (0.54) | LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4 | |
| SCHEMBL7885872 | 0.87 | CYP4F2 (0.61) | LOXL2CYP4F2CYP4A11SLC7A5RAB9A | |
| SCHEMBL8057216 | 0.86 | SLC7A5 (0.57) | LOXL2CYP4F2CYP4A11SLC7A5RAB9A | |
| SCHEMBL30489978 | 0.86 | SLC7A5 (0.57) | LOXL2SLC7A5MRGPRX4RAB9ASMN1; SMN2 | |
| SCHEMBL479999 | 0.86 | SLC7A5 (0.57) | LOXL2SLC7A5MRGPRX4RAB9ASMN1; SMN2 | |
| SCHEMBL3625604 | 0.86 | LOXL2 (0.68) | LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4 | |
| SCHEMBL1492405 | 0.86 | LOXL2 (0.68) | LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4 | |
| SCHEMBL29346854 | 0.86 | SLC7A5 (0.58) | LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4 | |
| SCHEMBL29214273 | 0.86 | LOXL2 (0.59) | LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4 | |
| SCHEMBL31068535 | 0.86 | SLC7A5 (0.58) | LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549010-B | Preparation and application of compound with AMPK (AMPK) agonistic activity and prodrug thereof | 中国科学院上海药物研究所 | 2023-10-20 | — | — | CN | disclosed |
| US-20230303872-A1 | INK, INK SET, SET OF INK AND PRE-PROCESSING FLUID, METHOD OF DISCHARGING INK, AND INK DISCHARGING DEVICE | RICOH COMPANY, LTD. (JP) | 2023-09-28 | — | — | US | disclosed |
| US-20230161246-A1 | RESIST UNDERLAYER FILM-FORMING COMPOSITION | NISSAN CHEMICAL CORPORATION (JP) | 2023-05-25 | — | — | US | disclosed |
| US-11649365-B2 | Ink, ink set, ink container, method of printing, and printing device | RICOH COMPANY, LTD. (JP) | 2023-05-16 | — | — | US | disclosed |
| CN-110467531-B | Preparation method of 3 '-nitro-2' -hydroxybiphenyl-3-formic acid | 新发药业有限公司 | 2022-04-19 | — | — | CN | disclosed |
| US-20220017764-A1 | INK, INK SET, INK CONTAINER, METHOD OF PRINTING, AND PRINTING DEVICE | RICOH COMPANY, LTD. (JP) | 2022-01-20 | — | — | US | disclosed |
| CN-113549010-A | Preparation and application of compound with AMPK agonistic activity and prodrug thereof | 中国科学院上海药物研究所 | 2021-10-26 | — | — | CN | disclosed |
| US-20170066712-A1 | NOVEL MOLECULES THAT SELECTIVELY INHIBIT HISTONE DEACETYLASE 6 RELATIVE TO HISTONE DEACETYLASE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-03-09 | — | — | US | disclosed |
| US-20170066712-A1 | NOVEL MOLECULES THAT SELECTIVELY INHIBIT HISTONE DEACETYLASE 6 RELATIVE TO HISTONE DEACETYLASE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-03-09 | — | — | US | disclosed |
| US-20170066712-A1 | NOVEL MOLECULES THAT SELECTIVELY INHIBIT HISTONE DEACETYLASE 6 RELATIVE TO HISTONE DEACETYLASE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-03-09 | — | — | US | disclosed |
| EP-1230863-A2 | Porous element | Filtrona Richmond, Inc. (US) | 2002-08-14 | — | — | EP | disclosed |
| EP-0881889-A4 | POLYETHYLENE TEREPHTHALATE SHEATH/THERMOPLASTIC POLYMER CORE BICOMPONENT FIBERS, METHOD OF MAKING SAME AND PRODUCTS FORMED THEREFROM | AMERICAN FILTRONA CORP (GB) | 2000-01-05 | — | — | EP | disclosed |
| EP-0881889-A1 | POLYETHYLENE TEREPHTHALATE SHEATH/THERMOPLASTIC POLYMER CORE BICOMPONENT FIBERS, METHOD OF MAKING SAME AND PRODUCTS FORMED THEREFROM | Filtrona International Limited (GB) | 1998-12-09 | — | — | EP | disclosed |
| US-5633082-A | FORM SELF-SUSTAINING THREE-DIMENSIONAL POROUS ELEMENTS USEFUL AS INK RESERVOIRS | AMERICAN FILTRONA CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| US-5620641-A | Polyethylene terephthalate sheath/thermoplastic polymer core bicomponent fibers, method of making same and products formed therefrom | AMERICAN FILTRONA CORPORATION (US) | 1997-04-15 | — | — | US | disclosed |
| US-5607766-A | FILTER, WICK | AMERICAN FILTRONA CORPORATION (US) | 1997-03-04 | — | — | US | disclosed |
| WO-1996039054-A1 | POLYETHYLENE TEREPHTHALATE SHEATH/THERMOPLASTIC POLYMER CORE BICOMPONENT FIBERS, METHOD OF MAKING SAME AND PRODUCTS FORMED THEREFROM | FILTRONA INTERNATIONAL LIMITED (GB) | 1996-12-12 | — | — | WO | disclosed |
| EP-0509769-B1 | Heterocyclic amides having HLE inhibiting activity | ZENECA LTD (GB) | 1996-09-11 | — | — | EP | disclosed |
| US-5521179-A | Heterocyclic amides | ZENECA LIMITED (GB) | 1996-05-28 | — | — | US | disclosed |
| EP-0509769-A2 | Heterocyclic amides having HLE inhibiting activity | ZENECA LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170066712-A1 | NOVEL MOLECULES THAT SELECTIVELY INHIBIT HISTONE DEACETYLASE 6 RELATIVE TO HISTONE DEACETYLASE | HDAC7, HDAC3, HDAC8 | LOXL2 3106/4885CYP4F2 3819/4885CYP4A11 3040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.