Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31150031 | 0.92 | MAPT (0.48) | MAPTRXFP1TP53POLBTHRB | |
| SCHEMBL29645760 | 0.90 | MAPT (0.56) | MAPTRXFP1TP53POLBTHRB | |
| SCHEMBL29645503 | 0.89 | ADORA3 (0.49) | MAPTRXFP1TP53POLBTHRB | |
| SCHEMBL29645502 | 0.89 | RXFP1 (0.41) | MAPTRXFP1TP53THRB | |
| SCHEMBL29645838 | 0.89 | MAPT (0.43) | MAPTRXFP1TP53POLBTHRB | |
| SCHEMBL29645571 | 0.88 | MAPT (0.46) | MAPTRXFP1TP53POLBTHRB | |
| SCHEMBL29645968 | 0.88 | MAPT (0.48) | MAPTRXFP1TP53POLBTHRB | |
| SCHEMBL29645625 | 0.88 | MAPT (0.44) | MAPTRXFP1TP53POLBTHRB | |
| SCHEMBL29645859 | 0.88 | MAPT (0.44) | MAPTRXFP1TP53POLBTHRB | |
| SCHEMBL29645485 | 0.88 | MAPT (0.44) | MAPTRXFP1TP53POLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |