Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 4/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | C1R | P00736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979910 | 1.00 | PLAT (0.38) | PLATDDB1CRBNSCN9AMGLL | |
| SCHEMBL29645983 | 0.95 | DDB1 (0.35) | PLATDDB1CRBNSCN9AMGLL | |
| SCHEMBL22978959 | 0.95 | DDB1 (0.35) | PLATDDB1CRBNSCN9AMGLL | |
| SCHEMBL22979265 | 0.94 | DDB1 (0.35) | PLATDDB1CRBNSCN9AMGLL | |
| SCHEMBL29648750 | 0.94 | DDB1 (0.35) | PLATDDB1CRBNSCN9AMGLL | |
| SCHEMBL22987860 | 0.91 | PLAT (0.35) | PLATDDB1CRBNSCN9AMGLL | |
| SCHEMBL22980841 | 0.88 | PLAT (0.40) | PLATDDB1CRBNSCN9AMGLL | |
| SCHEMBL29645644 | 0.88 | PLAT (0.40) | PLATDDB1CRBNSCN9AMGLL | |
| SCHEMBL22980169 | 0.85 | TACR1 (0.32) | SCN9A | |
| SCHEMBL22978985 | 0.85 | TACR1 (0.32) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |