Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 4/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | LITAF | Q99732 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.30 |
| ▸ | ACP1 | P24666 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979265 | 1.00 | DDB1 (0.35) | DDB1CRBNPLATS1PR1MGLL | |
| SCHEMBL22978959 | 0.98 | DDB1 (0.35) | DDB1CRBNPLATS1PR1MGLL | |
| SCHEMBL29645983 | 0.98 | DDB1 (0.35) | DDB1CRBNPLATS1PR1MGLL | |
| SCHEMBL22979910 | 0.94 | PLAT (0.38) | DDB1CRBNPLATS1PR1MGLL | |
| SCHEMBL29645529 | 0.94 | PLAT (0.38) | DDB1CRBNPLATS1PR1MGLL | |
| SCHEMBL22978985 | 0.90 | TACR1 (0.32) | SCN9AHCRTR1HCRTR2 | |
| SCHEMBL29648710 | 0.90 | TACR1 (0.32) | SCN9AHCRTR1HCRTR2 | |
| SCHEMBL29648704 | 0.90 | TACR1 (0.32) | SCN9AHCRTR1HCRTR2 | |
| SCHEMBL22980169 | 0.90 | TACR1 (0.32) | SCN9AHCRTR1HCRTR2 | |
| SCHEMBL22987860 | 0.89 | PLAT (0.35) | DDB1CRBNPLATMGLLADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |