Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979401 | 1.00 | MAPT (0.42) | MAPTTHRBSMN1; SMN2RXFP1PLAT | |
| SCHEMBL22979080 | 0.89 | MAPT (0.42) | MAPTTHRBSMN1; SMN2RXFP1PLAT | |
| SCHEMBL29648696 | 0.89 | MAPT (0.42) | MAPTTHRBSMN1; SMN2RXFP1PLAT | |
| SCHEMBL22979373 | 0.88 | CYP1A2 (0.41) | MAPTTHRBSMN1; SMN2RXFP1GAA | |
| SCHEMBL22979231 | 0.88 | CYP1A2 (0.41) | MAPTTHRBSMN1; SMN2RXFP1GAA | |
| SCHEMBL29645531 | 0.88 | CYP1A2 (0.41) | MAPTTHRBSMN1; SMN2RXFP1GAA | |
| SCHEMBL29646458 | 0.88 | CYP1A2 (0.41) | MAPTTHRBSMN1; SMN2RXFP1GAA | |
| SCHEMBL22981147 | 0.88 | CYP1A2 (0.41) | MAPTTHRBSMN1; SMN2RXFP1GAA | |
| SCHEMBL29645938 | 0.88 | CYP1A2 (0.41) | MAPTTHRBSMN1; SMN2RXFP1GAA | |
| SCHEMBL22979282 | 0.88 | MAPT (0.53) | MAPTTHRBSMN1; SMN2RXFP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |