Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | PTGFR | P43088 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645710 | 1.00 | LMNA (0.40) | LMNAGAAALPLKMT2AALPI | |
| SCHEMBL22981252 | 1.00 | LMNA (0.40) | LMNAGAAALPLKMT2AALPI | |
| SCHEMBL22979832 | 1.00 | LMNA (0.40) | LMNAGAAALPLKMT2AALPI | |
| SCHEMBL22979834 | 1.00 | LMNA (0.40) | LMNAGAAALPLKMT2AALPI | |
| SCHEMBL29645432 | 0.90 | TP53 (0.42) | LMNAGAAALPLKMT2AALPI | |
| SCHEMBL29646172 | 0.90 | TP53 (0.42) | LMNAGAAALPLKMT2AALPI | |
| SCHEMBL22979291 | 0.90 | TP53 (0.42) | LMNAGAAALPLKMT2AALPI | |
| SCHEMBL22979288 | 0.90 | TP53 (0.42) | LMNAGAAALPLKMT2AALPI | |
| SCHEMBL22981120 | 0.90 | TP53 (0.42) | LMNAGAAALPLKMT2AALPI | |
| SCHEMBL22981167 | 0.90 | MAPT (0.43) | LMNAGAAALPLKMT2AALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |