Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22988434 | 1.00 | PLAT (0.30) | PLATSLC5A1S1PR2 | |
| SCHEMBL29645746 | 0.92 | JAK2 (0.30) | — | |
| SCHEMBL22988435 | 0.92 | JAK2 (0.30) | — | |
| SCHEMBL22979089 | 0.90 | TACR1 (0.34) | — | |
| SCHEMBL29648738 | 0.90 | TACR1 (0.34) | — | |
| SCHEMBL22979156 | 0.86 | NR1H2 (0.37) | — | |
| SCHEMBL29646197 | 0.86 | NR1H2 (0.37) | — | |
| SCHEMBL29449970 | 0.84 | PCSK9 (0.32) | — | |
| SCHEMBL22988083 | 0.83 | TRPC3 (0.35) | — | |
| SCHEMBL22988358 | 0.82 | MAPT (0.36) | PLATSLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |