Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 9/20 | 0.34 |
| ▸ | TACR2 | P21452 | 8/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979089 | 1.00 | TACR1 (0.34) | TACR1TACR2ADORA2AADORA1KCNH2 | |
| SCHEMBL29648590 | 0.92 | ADORA2A (0.34) | TACR1TACR2ADORA2AADORA1KCNH2 | |
| SCHEMBL22988429 | 0.92 | ADORA2A (0.34) | TACR1TACR2ADORA2AADORA1KCNH2 | |
| SCHEMBL29648704 | 0.91 | TACR1 (0.32) | TACR1TACR2NPC1RAB9A | |
| SCHEMBL22978985 | 0.91 | TACR1 (0.32) | TACR1TACR2NPC1RAB9A | |
| SCHEMBL22980169 | 0.91 | TACR1 (0.32) | TACR1TACR2NPC1RAB9A | |
| SCHEMBL29648710 | 0.91 | TACR1 (0.32) | TACR1TACR2NPC1RAB9A | |
| SCHEMBL22988434 | 0.90 | PLAT (0.30) | — | |
| SCHEMBL29645872 | 0.90 | PLAT (0.30) | — | |
| SCHEMBL22988022 | 0.88 | MKNK1 (0.36) | TACR1TACR2ADORA2AADORA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |