Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.74 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.74 |
| ▸ | TNF | P01375 | 1/20 | 0.57 |
| ▸ | IL1B | P01584 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.57 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.57 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.53 |
| ▸ | GSK3B | P49841 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30087485 | 1.00 | CRBN (0.74) | CRBNDDB1TNFIL1BTBXA2R | |
| SCHEMBL22500886 | 0.92 | CRBN (0.75) | CRBNDDB1TNFIL1BTBXA2R | |
| SCHEMBL21062689 | 0.92 | CRBN (0.75) | CRBNDDB1TNFIL1BTBXA2R | |
| SCHEMBL20975160 | 0.92 | CRBN (0.75) | CRBNDDB1TNFIL1BTBXA2R | |
| SCHEMBL31655709 | 0.92 | CRBN (0.72) | CRBNDDB1TNFIL1BTBXA2R | |
| SCHEMBL29713150 | 0.91 | CRBN (0.73) | CRBNDDB1TNFIL1BTBXA2R | |
| SCHEMBL30281888 | 0.91 | CRBN (0.73) | CRBNDDB1TNFIL1BTBXA2R | |
| SCHEMBL30293948 | 0.91 | CRBN (0.73) | CRBNDDB1TNFIL1BTBXA2R | |
| SCHEMBL30293950 | 0.91 | CRBN (0.73) | CRBNDDB1TNFIL1BTBXA2R | |
| SCHEMBL29839634 | 0.91 | CRBN (0.73) | CRBNDDB1TNFIL1BTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |