Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979312 | 1.00 | ADORA2A (0.33) | ADORA2AADORA1PDE4BPDE7ABRD4 | |
| SCHEMBL22988475 | 0.90 | ADORA2A (0.35) | ADORA2AADORA1PIM1PIM2ADORA3 | |
| SCHEMBL22978983 | 0.89 | ADORA2A (0.34) | ADORA2AADORA1PIM1PIM2ADORA3 | |
| SCHEMBL22979849 | 0.89 | ADORA2A (0.34) | ADORA2AADORA1PDE4BPIM1PIM2 | |
| SCHEMBL29648773 | 0.89 | ADORA2A (0.34) | ADORA2AADORA1PDE4BPIM1PIM2 | |
| SCHEMBL22979348 | 0.88 | ADORA2A (0.34) | ADORA2AADORA1PIM1PIM2ADORA3 | |
| SCHEMBL22988432 | 0.88 | ADORA2A (0.33) | ADORA2AADORA1BRD4CREBBPPIM1 | |
| SCHEMBL29648628 | 0.88 | ADORA2A (0.33) | ADORA2AADORA1BRD4CREBBPPIM1 | |
| SCHEMBL22988214 | 0.88 | ADORA2A (0.38) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL29648715 | 0.88 | ADORA2A (0.38) | ADORA2AADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |