Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31150039 | 0.92 | MAPT (0.43) | MAPTTHRBPOLBADORA3NPC1 | |
| SCHEMBL29645636 | 0.88 | MAPT (0.47) | MAPTTHRBPOLBADORA3LMNA | |
| SCHEMBL29645568 | 0.85 | MAPT (0.35) | MAPTTHRBPOLBADORA3TP53 | |
| SCHEMBL29645518 | 0.85 | C1R (0.38) | MAPTTHRBPOLBTP53LMNA | |
| SCHEMBL29646071 | 0.85 | MAPT (0.45) | MAPTTHRBPOLBADORA3NPC1 | |
| SCHEMBL29645430 | 0.84 | NPC1 (0.48) | MAPTTHRBPOLBADORA3NPC1 | |
| SCHEMBL29645570 | 0.83 | MAPT (0.40) | MAPTTHRBPOLBADORA3ADK | |
| SCHEMBL29645760 | 0.81 | MAPT (0.56) | MAPTTHRBPOLBADORA3TP53 | |
| SCHEMBL29645843 | 0.81 | KMT2A (0.44) | MAPTTHRBPOLBADORA3TP53 | |
| SCHEMBL29645527 | 0.81 | MAPT (0.41) | MAPTPOLBTP53LMNAADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |