Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | C1R | P00736 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645636 | 0.88 | MAPT (0.47) | MAPTPOLBTHRBADKADORA3 | |
| SCHEMBL29645533 | 0.88 | MAPT (0.41) | NPC1RAB9AMAPTPOLBTHRB | |
| SCHEMBL29645843 | 0.88 | KMT2A (0.44) | MAPTPOLBTHRBADKADORA3 | |
| SCHEMBL29645527 | 0.88 | MAPT (0.41) | MAPTPOLBADKTP53 | |
| SCHEMBL29645608 | 0.87 | MAPT (0.40) | MAPTPOLBTHRBADKADORA3 | |
| SCHEMBL29645760 | 0.86 | MAPT (0.56) | MAPTPOLBTHRBADORA3ADORA1 | |
| SCHEMBL29646071 | 0.86 | MAPT (0.45) | NPC1RAB9AMAPTPOLBTHRB | |
| SCHEMBL29646060 | 0.85 | TP53 (0.47) | NPC1RAB9AMAPTPOLBTHRB | |
| SCHEMBL29645894 | 0.85 | KDM1A (0.40) | MAPTPOLBTHRBADKADORA3 | |
| SCHEMBL29646402 | 0.85 | ADK (0.42) | NPC1RAB9APDE10AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |