Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.33 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.33 |
| ▸ | CYP3A43 | Q9HB55 | 2/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22988279 | 1.00 | PAK1 (0.35) | PAK1KDM5ACYP1A2CYP3A4CYP3A5 | |
| SCHEMBL22979141 | 0.97 | KDM5A (0.35) | PAK1KDM5ACYP1A2CYP3A4CYP3A5 | |
| SCHEMBL22979232 | 0.90 | KDM5A (0.36) | PAK1KDM5ACYP1A2CYP3A4CYP3A5 | |
| SCHEMBL29645422 | 0.90 | CHEK1 (0.34) | — | |
| SCHEMBL22988494 | 0.90 | CHEK1 (0.34) | — | |
| SCHEMBL22988292 | 0.89 | CYP1A2 (0.33) | CYP1A2CYP3A4CYP3A5CYP3A7CYP2C19 | |
| SCHEMBL22979075 | 0.89 | PAK1 (0.34) | PAK1CYP1A2CYP3A4CYP3A5CYP3A7 | |
| SCHEMBL22988293 | 0.89 | CYP1A2 (0.33) | CYP1A2CYP3A4CYP3A5CYP3A7CYP2C19 | |
| SCHEMBL29646077 | 0.89 | PAK1 (0.34) | PAK1CYP1A2CYP3A4CYP3A5CYP3A7 | |
| SCHEMBL22979051 | 0.88 | KDM5A (0.38) | PAK1KDM5ACYP1A2CYP3A4CYP3A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |