Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.33 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.33 |
| ▸ | CYP3A43 | Q9HB55 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22988292 | 1.00 | CYP1A2 (0.33) | CYP1A2CYP3A4CYP3A5CYP3A7CYP2C19 | |
| SCHEMBL22979075 | 0.91 | PAK1 (0.34) | CYP1A2CYP3A4CYP3A5CYP3A7CYP2C19 | |
| SCHEMBL29646077 | 0.91 | PAK1 (0.34) | CYP1A2CYP3A4CYP3A5CYP3A7CYP2C19 | |
| SCHEMBL22987861 | 0.90 | ADORA3 (0.34) | PIM1 | |
| SCHEMBL22988299 | 0.90 | ADORA3 (0.34) | PIM1 | |
| SCHEMBL22979833 | 0.89 | MAP4K3 (0.32) | CYP1A2CYP3A4CYP3A5CYP3A7CYP2C19 | |
| SCHEMBL22979180 | 0.89 | MAP4K3 (0.32) | CYP1A2CYP3A4CYP3A5CYP3A7CYP2C19 | |
| SCHEMBL29645628 | 0.89 | MAP4K3 (0.32) | CYP1A2CYP3A4CYP3A5CYP3A7CYP2C19 | |
| SCHEMBL22988279 | 0.89 | PAK1 (0.35) | CYP1A2CYP3A4CYP3A5CYP3A7CYP2C19 | |
| SCHEMBL29645963 | 0.89 | PAK1 (0.35) | CYP1A2CYP3A4CYP3A5CYP3A7CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-13 | — | — | US | disclosed |
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | AHR, HRH4, HRH1 | CYP1A2 74/4885CYP3A4 374/4885CYP3A5 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.