Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 3/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31149972 | 0.92 | MAPT (0.54) | MAPTSMN1; SMN2THRBRXFP1POLB | |
| SCHEMBL29645482 | 0.91 | MAPT (0.53) | MAPTSMN1; SMN2THRBRXFP1POLB | |
| SCHEMBL29645544 | 0.91 | MAPT (0.53) | MAPTSMN1; SMN2THRBRXFP1POLB | |
| SCHEMBL29645822 | 0.90 | MAPT (0.47) | MAPTSMN1; SMN2THRBRXFP1POLB | |
| SCHEMBL29646058 | 0.90 | MAPT (0.47) | MAPTSMN1; SMN2THRBRXFP1POLB | |
| SCHEMBL29645487 | 0.90 | MAPT (0.59) | MAPTSMN1; SMN2THRBRXFP1POLB | |
| SCHEMBL29645542 | 0.88 | MAPT (0.46) | MAPTSMN1; SMN2THRBRXFP1TP53 | |
| SCHEMBL29646401 | 0.88 | MAPT (0.50) | MAPTSMN1; SMN2THRBRXFP1POLB | |
| SCHEMBL29645578 | 0.88 | MAPT (0.46) | MAPTSMN1; SMN2THRBRXFP1POLB | |
| SCHEMBL29645581 | 0.88 | MAPT (0.51) | MAPTSMN1; SMN2THRBRXFP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |