Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29646003 | 0.88 | MAPT (0.56) | MAPTSMN1; SMN2TP53RXFP1THRB | |
| SCHEMBL29645775 | 0.86 | MAPT (0.44) | MAPTSMN1; SMN2TP53RXFP1THRB | |
| SCHEMBL29645571 | 0.85 | MAPT (0.46) | MAPTSMN1; SMN2TP53RXFP1THRB | |
| SCHEMBL29645760 | 0.85 | MAPT (0.56) | MAPTSMN1; SMN2TP53RXFP1THRB | |
| SCHEMBL29645458 | 0.83 | MAPT (0.50) | MAPTSMN1; SMN2TP53RXFP1THRB | |
| SCHEMBL29645968 | 0.83 | MAPT (0.48) | MAPTSMN1; SMN2TP53RXFP1THRB | |
| SCHEMBL29645881 | 0.81 | RXFP1 (0.46) | MAPTSMN1; SMN2TP53RXFP1THRB | |
| SCHEMBL29645973 | 0.81 | TP53 (0.46) | MAPTSMN1; SMN2TP53RXFP1THRB | |
| SCHEMBL29645485 | 0.81 | MAPT (0.44) | MAPTSMN1; SMN2TP53RXFP1THRB | |
| SCHEMBL31149972 | 0.81 | MAPT (0.54) | MAPTSMN1; SMN2TP53RXFP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |