Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 5/20 | 0.33 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.33 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 3/20 | 0.32 |
| ▸ | JAK1 | P23458 | 3/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22988001 | 1.00 | NR1H2 (0.33) | NR1H2NR1H3PARP1TRPC3TRPC7 | |
| SCHEMBL22987658 | 0.93 | NR1H2 (0.37) | NR1H2NR1H3PARP1TRPC3TRPC7 | |
| SCHEMBL25118878 | 0.93 | NR1H2 (0.37) | NR1H2NR1H3PARP1TRPC3TRPC7 | |
| SCHEMBL22988171 | 0.93 | ADORA3 (0.35) | PARP1TRPC3TRPC7USP30GABRA5 | |
| SCHEMBL22988242 | 0.93 | USP30 (0.33) | NR1H2NR1H3PARP1USP30TP53 | |
| SCHEMBL22987728 | 0.93 | USP30 (0.33) | NR1H2NR1H3PARP1USP30TP53 | |
| SCHEMBL22987791 | 0.93 | TRPC3 (0.33) | NR1H2NR1H3PARP1TRPC3TRPC7 | |
| SCHEMBL25118615 | 0.92 | JAK2 (0.34) | PARP1TRPC3TRPC7USP30TP53 | |
| SCHEMBL25118622 | 0.92 | USP30 (0.32) | NR1H2NR1H3PARP1USP30TP53 | |
| SCHEMBL22988270 | 0.91 | USP30 (0.34) | NR1H2NR1H3PARP1TRPC3TRPC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |