Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22978988 | 1.00 | ADORA2A (0.38) | ADORA2AADORA1ADORA3ADORA2BAXL | |
| SCHEMBL29648550 | 0.91 | ADORA2A (0.37) | ADORA2AADORA1ADORA3ADORA2BSCN9A | |
| SCHEMBL22979168 | 0.91 | ADORA2A (0.37) | ADORA2AADORA1ADORA3ADORA2BSCN9A | |
| SCHEMBL29645871 | 0.91 | ADORA2A (0.37) | ADORA2AADORA1ADORA3ADORA2BSCN9A | |
| SCHEMBL22979210 | 0.91 | ADORA1 (0.37) | ADORA2AADORA1ADORA3ADORA2BSCN9A | |
| SCHEMBL29648566 | 0.91 | ADORA1 (0.37) | ADORA2AADORA1ADORA3ADORA2BSCN9A | |
| SCHEMBL22980138 | 0.91 | ADORA2A (0.37) | ADORA2AADORA1ADORA3ADORA2BSCN9A | |
| SCHEMBL22980928 | 0.91 | ADORA2A (0.37) | ADORA2AADORA1ADORA3ADORA2BSCN9A | |
| SCHEMBL22979037 | 0.91 | ADORA1 (0.37) | ADORA2AADORA1ADORA3ADORA2BSCN9A | |
| SCHEMBL29648570 | 0.91 | ADORA2A (0.37) | ADORA2AADORA1ADORA3ADORA2BSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |