Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 9/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979037 | 1.00 | ADORA1 (0.37) | ADORA1ADORA2AADORA3ADORA2BCHEK1 | |
| SCHEMBL22979210 | 1.00 | ADORA1 (0.37) | ADORA1ADORA2AADORA3ADORA2BCHEK1 | |
| SCHEMBL29646475 | 1.00 | ADORA1 (0.37) | ADORA1ADORA2AADORA3ADORA2BCHEK1 | |
| SCHEMBL22988306 | 0.98 | ADORA2A (0.35) | ADORA1ADORA2AADORA3ADORA2BCHEK1 | |
| SCHEMBL29645819 | 0.94 | SCN9A (0.35) | ADORA1ADORA2AADORA3ADORA2BCHEK1 | |
| SCHEMBL22979965 | 0.94 | SCN9A (0.35) | ADORA1ADORA2AADORA3ADORA2BCHEK1 | |
| SCHEMBL22988474 | 0.91 | ADORA2A (0.34) | ADORA1ADORA2AADORA3ADORA2BSCN9A | |
| SCHEMBL22978988 | 0.91 | ADORA2A (0.38) | ADORA1ADORA2AADORA3ADORA2BSCN9A | |
| SCHEMBL29646141 | 0.91 | ADORA2A (0.38) | ADORA1ADORA2AADORA3ADORA2BSCN9A | |
| SCHEMBL22978999 | 0.91 | PIM1 (0.35) | ADORA1ADORA2AADORA3ADORA2BSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |