Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 7/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CCNK | O75909 | 1/20 | 0.31 |
| ▸ | CDK7 | P50613 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | CCNH | P51946 | 1/20 | 0.31 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.31 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22988129 | 1.00 | PIM1 (0.33) | PIM1PDE3BPDE3APIM3PIM2 | |
| SCHEMBL22988486 | 0.91 | PIM1 (0.34) | PIM1PIM3PIM2CCNT1CCNK | |
| SCHEMBL29645793 | 0.91 | CCNK (0.38) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL22988396 | 0.91 | CCNK (0.38) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL22979685 | 0.90 | PIM1 (0.34) | PIM1PDE3BPDE3APIM3PIM2 | |
| SCHEMBL22979188 | 0.90 | PIM1 (0.34) | PIM1PIM3PIM2 | |
| SCHEMBL29646112 | 0.90 | PIM1 (0.34) | PIM1PIM3PIM2 | |
| SCHEMBL29645885 | 0.90 | PIM1 (0.34) | PIM1PIM3PIM2ADORA2AADORA2B | |
| SCHEMBL22979833 | 0.89 | MAP4K3 (0.32) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL22979392 | 0.89 | PDE3B (0.33) | PDE3BPDE3ACCNT1CCNKCDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |