Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30598302 | 1.00 | S1PR4 (0.36) | S1PR4S1PR1S1PR3S1PR5HRH2 | |
| SCHEMBL30598274 | 1.00 | S1PR4 (0.36) | S1PR4S1PR1S1PR3S1PR5HRH2 | |
| SCHEMBL27393425 | 0.88 | HRH2 (0.41) | S1PR4S1PR1S1PR3S1PR5HRH2 | |
| SCHEMBL24960426 | 0.88 | HRH2 (0.41) | S1PR4S1PR1S1PR3S1PR5HRH2 | |
| SCHEMBL30598272 | 0.88 | HRH2 (0.41) | S1PR4S1PR1S1PR3S1PR5HRH2 | |
| SCHEMBL23107027 | 0.83 | TSHR (0.35) | HRH2HRH1HRH3 | |
| SCHEMBL3478365 | 0.83 | TSHR (0.35) | HRH2HRH1HRH3 | |
| SCHEMBL24662659 | 0.83 | TSHR (0.35) | HRH2HRH1HRH3 | |
| SCHEMBL29680322 | 0.79 | HRH2 (0.33) | HRH2HRH1HRH3 | |
| SCHEMBL4473520 | 0.79 | MAOB (0.44) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022059684-A1 | VITAMIN D DERIVATIVE HAVING CYCLIC AMINE IN SIDE CHAIN | 帝人ファーマ株式会社 | 2022-03-24 | — | — | WO | disclosed |