Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979870 | 1.00 | MAPT (0.48) | MAPTTHRBADORA3GAATP53 | |
| SCHEMBL29648930 | 0.96 | MAPT (0.45) | MAPTTHRBADORA3GAATP53 | |
| SCHEMBL22987541 | 0.95 | MAPT (0.43) | MAPTTHRBADORA3GAATP53 | |
| SCHEMBL22987524 | 0.94 | ADORA3 (0.42) | MAPTTHRBADORA3SMN1; SMN2ADORA2A | |
| SCHEMBL22987564 | 0.93 | ADORA3 (0.44) | MAPTTHRBADORA3GAATP53 | |
| SCHEMBL22987447 | 0.93 | MAPT (0.43) | MAPTTHRBADORA3GAATP53 | |
| SCHEMBL22987605 | 0.93 | MAPT (0.41) | MAPTTHRBADORA3GAATP53 | |
| SCHEMBL22987566 | 0.93 | MAPT (0.41) | MAPTTHRBADORA3GAATP53 | |
| SCHEMBL22987525 | 0.93 | ADORA3 (0.45) | MAPTTHRBADORA3GAASMN1; SMN2 | |
| SCHEMBL22979112 | 0.92 | MAPT (0.49) | MAPTTHRBGAATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |