Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979544 | 1.00 | C1R (0.42) | C1RADORA3ADORA1PDE10AHPGD | |
| SCHEMBL22988173 | 0.91 | ADORA3 (0.41) | C1RADORA3ADORA1PDE10AHCAR1 | |
| SCHEMBL22987590 | 0.90 | ADORA3 (0.41) | C1RADORA3ADORA1MAPT | |
| SCHEMBL22987958 | 0.90 | ADORA3 (0.39) | C1RADORA3ADORA1PDE10AHCAR1 | |
| SCHEMBL22987582 | 0.90 | ADORA3 (0.40) | ADORA3ADORA1HPGDMAPT | |
| SCHEMBL22987584 | 0.89 | ADORA3 (0.40) | C1RADORA3ADORA1MAPT | |
| SCHEMBL22987661 | 0.88 | ADORA3 (0.40) | C1RADORA3ADORA1PDE10AMGLL | |
| SCHEMBL22987592 | 0.87 | MCHR1 (0.39) | C1RADORA3ADORA1 | |
| SCHEMBL22987511 | 0.85 | ADORA3 (0.45) | C1RADORA3ADORA1PDE10AMAPT | |
| SCHEMBL25118631 | 0.85 | CYP1A2 (0.49) | C1RADORA3ADORA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |